Cisplatin is a chemotherapy medication used to treat a number of different cancers. Cisplatin is administered through a vein as an infusion (IV). One of
the side effects of cisplatin is kidney toxicity, which can potentially lead to renal (kidney) failure. The kidneys perform many crucial functions for the
human body, one of them including maintaining water balance. Kidney cells do this by absorbing water from urine before it is excreted from the body.
Researchers examined the urinary flow rate (the amount of urine produced per hour) of individuals after treatment with various concentrations of
cisplatin. The results are in the table below.