Computer Configuration policies (also called Machine policies) are enforced for the entire computer and are applied when the computer boots.
Computer Configuration policies include:
Software that should be installed on a specific computer
Scripts that should run at startup or shutdown
Password restrictions that must be met for all user accounts
Network communication security settings
Registry settings that apply to the computer (the HKEY_LOCAL_MACHINE subtree)
Computer Configuration policies are initially applied as the computer boots and are enforced before any user logs on.