during transcription in _______ cells, transcriptional regulators that bind to DNA thousands of nucleotides away from a gene;s promoter can affect a gene's DNA thousands of nucleotides away from a gene's promoter can affect a gene's transcription. The ________ is a complex of proteins that links distantly bound transcription regulators with the proteins bound closer to the transcriptional start site. Transcriptional activators can also interact with histone ______, which alter chromatin by modifying lysines in the tail of histone proteins to allow greater accessibility to the underlying DNA. gene repressor proteins can reduce the efficiency of transcription initiation by attracting _________ . Sometimes, many contigous genes can become transcriptionally inactive as a result of chromatin remodeling, like the ___________ found in interphase chromosomes.