QUESTION 5 Which of the following is a disadvantage of an intrauterine device (IUD)? A. It cannot be used by breastfeeding women. B. Side effects may include acne, breast tenderness, and uterine cramps. OC. After removal, it usually takes up to six months to return to fertility. Upon initial insertion, it usually takes up to one week to work, so an alternative method of contraception is needed during that time.