A 42-year-old mildly overweight man is being evaluated for his second episode of deep vein thrombosis in 2 years. Both episodes appear to have been unprovoked. He has no recent prolonged immobility, long-distance travel, or lower-extremity trauma. The patient has no past medical history of diabetes, cancer, or liver disease. A thrombophilia workup is ordered. Use of which of the following drugs is most likely to lead to low protein S levels?
A)Aspirin
B)Clopidogrel
C)Heparin
D)Simvastatin
E)Warfarin