jordnnnn4935 jordnnnn4935

22-01-2024
Medicine

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Nitroglycerin undergoes first-pass effect and thereby given as a sublingual formulation whereas some drugs undergo enterohepatic circulation and never reach site of action. The first-pass effect primarily alters a drug's _ whereas enterohepatic circulation alters a drug's __.
A. Absorption, metabolism
B. Distribution, metabolism
C. Metabolism, distribution
D. Metabolism, excretion

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