While caring for an older adult patient with respiratory problems, the nurse teaches the patient about the effective use of an inhaler. Which instruction given by the nurse would be most appropriate if a pressurized metered-dose inhaler was prescribed to the patient?

1. Coordinate the puffs with inhalation for effective outcome.
2. Inspire fast enough to administer the entire dose of the medication.
3. Place the medication away from humidity, as there is a chance for formation of clumps.
4. Apply approximately 5 to 10 lbs of pressure to the top of the canister to administer the medication.