Autophagy protein ATG-16.2 and its WD40 domain mediate the beneficial effects of inhibiting early-acting autophagy genes in C. elegans neurons.
a) Explain the role of ATG-16.2 in autophagy.
b) Discuss the significance of WD40 domain in autophagy regulation.
c) Elaborate on the beneficial effects of inhibiting early-acting autophagy genes.
d) Provide alternative approaches to enhance autophagy in neurons.