Which of the following statements accurately reflects the role of AM404 in the endocannabinoid system?
A) AM404 directly activates CB1 receptors, leading to increased inflammation and perception of pain.
B) AM404 inhibits the re-uptake of anandamide (AEA) into neurons and astrocytes, prolonging its activity and enhancing pain relief through CB1 receptors.
C) AM404 is an enzyme responsible for breaking down epinephrine after their required response in pain regulation.
D) AM404 primarily acts by inhibiting COX-2, independent of its interaction with the CB1 receptor and endocannabinoid system.