A 78-year-old male waited at the emergency room (ER) one night with complaints of a sore throat and runny nose. He informed the doctor of having a weak immune system. The doctor diagnosed him with minor flu and sent him home with medication. The following morning, he dies. What is a POSSIBLE explanation?
A. Due to having a weak immune system, he acquired a local infection from another pathogen at the ER. High levels of TNF-α being released locally in his body blocked the delivery of essential nutrients to organs and caused septic shock, resulting in his death
B. Due to having a weak immune system, he acquired a systemic infection from another pathogen at the ER. High levels of TNF-α being released systemically in his body blocked the delivery of essential nutrients to organs and caused septic shock, resulting in his death
C. Due to having a weak immune system, he acquired a systemic infection from another pathogen at the ER. High levels of IFN-α and IFN-β activated too many NK cells which started to kill his brain cells, resulting in his death
D. Due to having a weak immune system, he acquired a systemic infection from another pathogen at the ER. High levels of C5b caused the perforation of pathogen cell membranes and started to perforate his healthy cells, resulting in his death
E. None of the above