Respuesta :

The answer is false.

Macrophage is one of the immune cells that comes from reticuloendhotelial system while the endothelial cells refer to the cell that lining inner part of the blood vessel. Endothelial cell is a single layer squamous cell that has main role in protecting the vessel physically. Macrophage has a role in immunity function.

Endothelial cells give rise to macrophages after entering the extra vascular tissue. This statement is false.

Further Explanation:

Vasoactive factors are the chemical mediators released by the endothelium cells of the blood vessels. Histamine and prostaglandins stimulate vasodilation (widening of the blood vessels) because of muscular walls relaxation surrounding the blood vessels. Bradykinin promotes extravasation (movement of neutrophils out of blood vessels) by loosening the endothelial cell junctions.

Reticulocyte enters into the sinusoidalextravascular sites leads to the formation of the macrophages. These macrophages kill the foreign invaders directly by phagocytosis. In adaptive immunity, they present bacterial antigens on their cell surface, hence named as Antigen Presenting Cells (APCs). Thus, it can be concluded that macrophages are not synthesized by the endothelial cell. The macrophages get accumulated in the infected area during inflammation. The macrophages residing in the bloodstream engulf the microbes and release some vasoactive factors (leukotrienes, prostaglandins, and platelet-activating factor). They cause an increase in vasodilation and vascular permeability.  

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Answer Details:

Grade: High School

Subjects: Biology

Chapter: Immunology

Keywords:

Macrophages, antigen, activating factor, permeability, cell surface, antigen, reticulocyte, phagocytosis, prostaglandins, leukotriene.

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