Which of the following statements is true regarding T cell receptors? (Select all that apply.) They are formed by the rearrangement of V, J, C, and D gene segments. They contain variable and constant regions. They can be found in the bloodstream independent of T cells. They recognize antigen-MHC complexes. They are composed of two heavy (H) chains and two light (L) chains.

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24-11-2018
Biology

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Which of the following statements is true regarding T cell receptors? (Select all that apply.) They are formed by the rearrangement of V, J, C, and D gene segments. They contain variable and constant regions. They can be found in the bloodstream independent of T cells. They recognize antigen-MHC complexes. They are composed of two heavy (H) chains and two light (L) chains.

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Xema8 Xema8 · Answer 1 · 2018-12-05T17:43:36+01:00

The true statements about he T cell receptors are 1, 2 and 4.

T cell receptors are the molecules found on the surface of the T lymphocytes. V(D)J recombination is the unique mechanism of genetic recombination that occurs only in the lymphocytes during the early stages of T and B cell maturation resulting in the T cell receptors. They recognize antigen fragments bound to MHC molecules. Majority of the T cell receptors consists of an alpha chain and a beta chain and a few with gamma and delta chains. Each chain is composed of a variable and a constant region. Within these chains are the complementary determining regions (CDRs) which determine the antigen to which the T cell receptor will bind.