Lady Macbeth is the main female protagonist of the play and is slowly losing her mind over her guilty conscience because of Duncan's Death. Thus, option D is accurate.
Who is Lady Macbeth?
Lady Macbeth is the wife of Macbeth and is a strong-willed woman who is just ruthless and inhumane. She pushes Macbeth to participate in killing King Duncan.
In act V, scene I, she is seen as deranged and weak as her conscience makes her feel guilty over Duncan's death. In this scene, the audience can see her state of mind as she sleepwalks.
Therefore, option D. Lady Macbeth felt guilty for participating in King Duncan's death.
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