Answer:
[tex]4.500\times 10^{2}[/tex]
Explanation:
Scientific notation is the way of writing numbers which are either large or small. The number is written in the scientific notation when the number is between 1 and 10 and then multiplied by the power of 10.
The given number:
450.0000345 can be written as [tex]4.500000345\times 10^{2}[/tex]
Answer upto 4 significant digits = [tex]4.500\times 10^{2}[/tex]