Answer:
p53 or Tumor protein (TP53 ) is the Guardian of genome. located on locus 17p13.1 on chromosomes
It is the gene that regulates the protein that codes for process of cell cycle of ( mitosis and meiosis)' and cell death therefore suppresses the uncontrollable cells growth which can lead to tumor.
TP53 has relatively high molecular mass of 53 kilodalton fractions in the cell ; this characteristics together with the ability to conserve cell cycle stability in multicellular organism by stopping mutation of genetic materials by suppressing tumor made it to be called the Guardian of genome.
ROLES
→ p53 functions by arresting the growth of cells to stop uncontrolled growth.
←it also repair damage DNA to guide against mutation, by activation of protein involved in DNA repair.
and
←Promotes death of the cells (Apoptosis,) so that damaged or altered DNA would not be transcript and translated in the cell.
