USDA-APHIS Animal Care Resource Policy #12 "Considerations of Alternatives to Painful/Distressful Procedures" states that when a database search is the primary means of considerations to alternatives of painful and distressful procedures, that a narrative should include all of the following except:
A. The name of the databases searched
B. The date the search was performed
C. The specific field of study
D. The search strategy (including scientifically relevant terminology) used
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C. The specific field of study
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Which of the following should be considered a significant change to an animal use proposal?
A. change in departmental affiliation of the principal investigator
B. change in start date of study
C. change in anesthetic agent
D. change in fluid administration
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C. change in anesthetic agent
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USDA-APHIS Animal Care Resource Policy #12 "Considerations of Alternatives to Painful/Distressful Procedures" states that when a database search is the primary means of considerations to alternatives of painful and distressful procedures, that a narrative should include all of the following except:
A. The name of the databases searched
B. The date the search was performed
C. The specific field of study
D. The search strategy (including scientifically relevant terminology) used

In the consideration for the procedure, some information are required and examples are the strategy of the search/the database name. However, the area of study is not one of the information.

The animal use proposal can general be altered based on the type of change required. However, an anesthetic agent alteration is not a significant change.

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