Correct answer: METABOLIC PATHWAYS
According to dictionary definition, metabolic pathways are sequences of biochemical reactions in living cells, driven along by enzymes, that mainly involve the exchange of energy and chemicals.
As for the specific discovery of metabolic pathways and enzyme involvement, we can look to Louis Pasteur in the 19th century, who noted that yeast changed sugar into alcohol by the catalyst of substances within the yeast cells that he termed "ferments." (Thus we speak of "fermentation.") In addition to Pasteur's discovery, Friedrich Wöhler published work in 1828 regarding the chemical synthesis of urea, which he discovered when he was trying to synthesize ammonium cyanate. These scientists were documenting the chemical reactions found in cells that we now refer to as metabolic pathways.
In the 20th century, Eduard Buchner furthered knowledge of metabolic pathways by the discovery of enzymes. This showed that studying the chemical reactions of metabolism was different from the biological study of cells.
