Answer:
is negative, except when there is a change in membrane permeability to ions
Explanation:
Membrane potential is voltage that result from differences in Ion concentration of cellular membrane.
Many Ions such as potassium(K+), Sodium(Na+)and chlorine(cl-) has many gradient across the membrane this gives the potential energy. If the membrane is permeable it gives rise to intake of potassium, leading to diffusion of positive charged Ion down the gradient outside the cell leading to a concentration of uncompensated net negative charge.
Hence, the membrane potential is mostly negative except there is a change in members permeability to Ion
