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Look at the following mutation: AUG-GUC-CCU-AAA → AUG-AGU-CCC-UAA-A. The base A was inserted following the start codon AUG. Describe how this mutation affects the encoded amino acid sequence.

Respuesta :

Answer: Non sense mutation took place over here.

Explanation:

Mutation took place over here where, the base A was inserted in place of the start codon AUG.

This states that the last codon will code for a stop signal instead of amino acid.

This is a type of non sense mutation when the ribosome is stopped from reading a stretch of mRNA because a stop codon is present over there.

The original set of codon is replaced by the stop codon and the protein synthesis is stopped.

When there is an alteration in the genetic bases of codes that can lead to modification in the phenotype or the genotype of an organism is called a mutation.

The type of mutation that occurred in the given sequence is a non-sense mutation.

The mutation can be explained as:

  • The mutation changed the reading frame of the triplets from the second place after the AUG or the start codon.

  • The last codon in the unmutated sequence AAA was for lysine (lys) but in the mutated sequence is changed to UAA (stop codon) which codes for the termination of the chain.

  • The mutation in stop codons are called non-sense mutation and now it will signal for termination instead of coding for another amino acid.

  • When the process of translation gets terminated and the ribosomes stop translating due to mutation then it is called a nonsense mutation.

Therefore, the process will terminate due to replacement by a stop codon.

To learn more about non-sense mutation follow the link:

https://brainly.com/question/20695024

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