Your friend can either mean by Pepe the frog. (A cartoon frog called pepe which is I guess a meme) or an origin: Boys club "My Pepe philosophy is simple: 'Feels good man. ' It is based on the meaning of the word Pepe: 'To go Pepe'.
Is your friend filipino? If he says “pepe” he probably meant vagina ^•^ but “pepe” is also a name for a little boy in Tagalog. There’s a lot of term used for pepe in Tagalog soooo hope this helps :)
