When catecholamine or peptide hormone binds to receptors on the surface of a cell - a second messenger appears in the cytoplasm.
Protein and peptide hormones, catecholamines such as epinephrine, and eicosanoids have their receptors present on the plasma membrane of target cells.
Thus, when catecholamine or peptide hormone binds to receptors on the surface of a cell - a second messenger appears in the cytoplasm.
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