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Most women experience their final menstrual cycle around the age of 51. The ceasing of the menstrual cycle is called menopause, and it signals the end of a woman’s reproductive years. It’s triggered by a change in hormone levels and a decline in oocytes. Doctors can perform a test to check a woman’s hormone levels to determine if menopause has occurred. If the woman is in menopause, the test will reveal high FSH levels and low estrogen levels.

How could a decline in the number of oocytes contribute to this change in hormones?

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Oocytes produce estrogen, when there are fewer oocytes it'll drop in estrogen levels in  the blood. Estrogen and FSH work on negative feedback, one of the hormones that control the release of estrogen. If estrogen is naturally dropping near menopause it will release more FSH, which will cause higher levels of FSH in the blood.

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