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Charcot-Marie-Tooth is a muscular wasting disease that affects 1 in 2,500 people. Researchers have discovered that this occurs when a large gene on the short arm (p-arm) of chromosome number 17 makes a new copy of itself. What kind of chromosomal mutation is this?

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Answer:

Type X Charcot-Marie-Tooth disease (CMTX) is caused by mutations in genes on the X chromosome, one of the two sex chromosomes. Within the various types of Charcot-Marie-Tooth disease, subtypes (such as CMT1A, CMT1B, CMT2A, CMT4A, and CMTX1) indicate different genetic causes.

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