Across
4. Drug
9. Fetal alcohol syndrome
11. Detoxification
12. Fermentation
13. Blackout
14. Refusal skills
15. Overdose
Down
1. Addiction
2. Intoxication
3. Binge drinking
5. Cirrhosis
6. Tolerance
7. Depression
8. Hangover
10. Rehabilitation
Pretty sure this is right :) Hope this helps!