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1.Explain how the TATA box and transcription
factors work together to ensure that RNA
polymerase is transcribing the correct region of the
DNA molecule

Respuesta :

learnlikenamjoon

Answer:

The TATA box is an alternating sequence of Adenine and Guanine nucleotides that transcription factors bind to. The TATA box is found just before a gene. The transcription factors tell the RNA polymerase where to bind to begin transcription. This ensures the RNA polymerase will know where to start and which gene to transcribe.

Explanation:

luisvaschetto

In eukaryotes, the TBP protein binds to the TATA box during the formation of the RNA pol complex, while transcription factors help to promote transcription.

  • The TATA box is a nucleotide (DNA) sequence located very proximal to the Transcriptional Start Site, within the promoter region of the eukaryotic genes.

  • This sequence (TATA box) binds to a specific transcription factor known as the TATA Binding Protein (TBP), which is required during the formation of the RNA polymerase (RNA pol) transcriptional complex.

  • Moreover, transcription factors are proteins that bind to different nucleotide sequences located at both the promoter and enhancer regions of genes, which are capable of promoting transcription.

  • For example, basal (general) transcription factors bind to the promoter region of eukaryotic genes to induce the attachment of the RNA pol, which is required to initiate transcription.

In conclusion, the TBP protein binds to the TATA box during the formation of the RNA pol complex, while transcription factors help to promote transcription.

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