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The fundamental explanation for the cause of cancer is that

cell replication becomes uncontrolled

viral or bacterial antigens infect a body that cannot destroy them

a recessive genetic disorder is expressed in both alleles

cells no longer replicate and become non-functioning

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HillbillyBioTeacher
Cell replication becomes uncontrolled. Cancer is defined as uncontrolled cell division. Hope this helps! -HBT
Greenleafable
The fundamental explanation for the cause of cancer is that cell replication becomes uncontrolled.
Some mutations can lead to uncontrolled and accelerated division of cells which create a tumor, and if it is not treated in time, it usually leads to death. 

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