A certain mutation in the gene for hemoglobin results in the red blood cells becoming sticky,
rigid, and irregularly shaped. These irregularly shaped red blood cells block the flow of blood
throughout the body. A single base mutation is responsible for these irregularly shaped blood cells.

Which of these mutations most likely results in the mutated hemoglobin gene?
F. Insertion
G. Deletion
H. Duplication
J. Substitution

Mutation in genes can result in different types of abnormalities. In gene related to hemoglobin makes RBCs sticky, irregular shaped, this is because of substitution.

What is substitution?

Mutation is a type of replication error during formation of new DNA.

In substitution mutation, incorrect nucleotide is placed at incorrect position during DNA replication, a point mutation occur in which a single nucleotide is substituted.

It actually does not add or remove any nucleotide from the sequence, just it substitute it.

In gene related to hemoglobin, the amino acid glutamic acid gets replaced with the valine amino acid at position 6 in beta-globin, which results in sticky, irregularly shaped red blood cells.

Thus the correct option is J.

For more details regarding substitution mutation, visit:

https://brainly.com/question/15204431