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The Native Americans responded to the Indian Removal Act of 1830 in different ways. Many of them left the surrounding of the Mississippi and moved to the West, in what was known as the Trail of Tears. Some others resisted the removal act as Cherokee Nation.

The Removal Act was signed under President Andrew Jackson in 1830.

Many Native Americans died along the journey of the movement into the West. Those that resisted engaged in wars against the United States.

Hence, in this case, it is concluded that the Indian Removal Act of 1830 led to the deaths of many Native Americans.

Learn more here: https://brainly.com/question/9367389

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