Muscle cells develop from embryonic precursor cells that have the potential to develop into a number of cell types. Which of the following best explains the particular conditions that commit them to becoming muscle cells? (1 point)
A. All the genetic material is transcribed, but only the genes required are translated.
B. Electrical signals are sent to the individual cells to turn on and off specific genes.
C. Signal cells send out chemical messages to nearby cells to change gene expression.
D. Specific cells have unique DNA that is only the portion re

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Answer:

-muscle precursor cells migrate from the somite to the regions of the embryo that will form muscles (limb buds)

-myogenic precursor cells express the paired homeodomain transcription factor, Pax3 and in some cases Pax7

-mutants lacking functional Pax3 have no limb muscles because of failure of muscle precursors to migrate from the somite to the limb bud

-Pax3/Pax7 positive cells are true stem cells in that they are capable of either self-renewal (proliferation) or differentiation to form committed muscle cells

Explanation: