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Nondisjunction mutation is the type of mutation that would a karyotype best help to discover when a scientist is using a karyotype to investigate a mutation in an organism.

An individual's entire set of chromosomes is known as their karyotype.

This can also be used to describe a lab-made representation of a person's chromosomes split from one cell and arranged in numerical order.

A karyotype can be used to check for chromosomal numbers or structural problems.

The missegregation of a homologous pair of chromosomes during meiosis is known as nondisjunction.

A new cell with an excessive amount of genetic material is created as a result. This kind of chromosomal mutation leads to a multitude of clinical problems.

An important example is Down's syndrome.

Trisomy of autosomes, or chromosome 21, is the cause of Down's syndrome.

Only one percent of instances had mosaicism along with Down's syndrome.

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