Respuesta :
The Kaposi's sarcoma-associated herpes virus was identified in a unique and unusual category of AIDS-related lymphomas that generally manifest as lymphomatous effusions with no apparent tumor tissues.
Description of the Statement-
- KSHV is consistently present in these body cavity-based lymphomas, and several other characteristics make them stand out.
- To test this theory, 19 malignant lymphomatous effusions that did not contain a contiguous tumor mass were examined for their symptomatic, cytologic, immunophenotypic, infectious, and molecular features.
- KSHV was found in 15 of the 19 lymphomas. The c-myc gene rearrangements and Burkitt-like morphology among all 4 KSHV-negative lymphomatous effusions suggested that these were Burkitt-type lymphomas developing in the bodily cavities.
- Furthermore, these lymphomas developed in men, usually but not always in connection with HIV infection, and homosexual behavior was a risk factor.
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