The blood used in the first transfusion contained Rh antigens, which caused the patient to produce anti-Rh antibodies and attack the blood from the second transfusion causing agglutination.
what is agglutination and why does it occur ?
A clumping of particles is called agglutination.
the clustering of cells, like bacteria or red blood cells, when an antibody or complement is involved. An extensive complex formed when an antibody or other molecule binds several particles and binds them altogether. Due to its ability to phagocytose large clusters of bacteria increase the effectiveness of microbial elimination through phagocytosis.
When the incorrect blood group is transfused into a person, the antibodies react with the transfused blood group, that causes the erythrocytes to clump and cling to one another, causing them to agglutinate.
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