Psychosocial factors associated with persistent pain in people with HIV: a systematic review with meta-analysis

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22-07-2022
Social Studies

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Psychosocial factors associated with persistent pain in people with HIV: a systematic review with meta-analysis

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Tutorconsortium351 Tutorconsortium351 · Answer 1 · 2022-07-30T12:33:21+02:00

Things like marital status, social support, bereavement, home and work environments, social status, and social integration are examples of psychosocial factors that may affect pain. For instance, a person who is under a lot of stress from their job or family life may have a reduced pain threshold.

Psychosocial factors associated with persistent pain in people with HIV?

Several psychosocial factors, including depression, psychologic distress, post-traumatic stress, drug abuse, sleep disturbance, reduced antiretroviral therapy adherence, healthcare use, missed HIV clinic visits, unemployment, and protective psychologic factors, were associated with pain outcomes in people with HIV, according to a meta-analysis and literature review published in the journal Pain.

In a sample of individuals with HIV and pain, researchers included 46 observational or experimental studies, of which 37 contributed data for the meta-analysis, reporting on the connection between more than one psychosocial factor and more than one pain-related variable.
The majority of the studies under review (83%) were carried out in the United States, and participants were primarily recruited through HIV clinics or using a variety of tactics, such as community outreach and recruitment from substance misuse clinics.
The investigations revealed that there was a lot of variation in how pain and psychosocial factors were measured. 63 percent of the studies were rated as medium quality by the researchers, two were rated as high quality, and 15 were rated as low quality. Additionally, they stated that the most typical flaws included ambiguous reporting of response rates, a lack of justification for sample size a priori, and inadequate reporting of HIV and pain characteristics.
For those with HIV, chronic pain continues to be a common and incapacitating issue in the era of antiretroviral therapy. Psychosocial interventions may be effective in reducing the effects of this discomfort. Research is necessary to pinpoint the psychosocial processes that these treatments should aim to address, though.
The evidence regarding psychosocial aspects related to pain, disability, and quality of life in people with HIV and persistent pain was evaluated in the current systematic review and meta-analysis. Studies that involved an adult sample of adults with HIV and pain and reported on the relationship between one or more psychosocial factors and one or more pain-related variables were acceptable.

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