Since antibiotics prevent bacterial growth and replication by interfering with the bacterial cell wall, peptidoglycan in the bacterial cell envelope makes a perfect target for them.
- One of the antibiotics that attack the bacterial cell wall in order to work is penicillin.
- The drugs specifically prevent the bacteria from forming peptidoglycan, a substance that provides their cell walls the tenacity they require to survive inside of humans.
- Simply put, many antibiotics, including vancomycin, which like beta-lactam antibiotics targets the peptidoglycan in the cell wall, are ineffective against
- Gram-negative bacteria because they do not possess the molecular characteristics required to effectively use these pathways to breach the outer membrane.
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