A horse and a donkey can reproduce successfully, producing a mule. however, the mule is sterile. this is an example of a postzygotic barrier called Reproductive isolation .
The mule is a hybrid between a donkey and a horse or pony. The diploid chromosome number in the donkey is 62 and in the horse or pony it is 64. The mule therefore has 63 chromosomes and is infertile. This is an example of a postzygotic isolating mechanism.
The mule is an example of an infertile hybrid. Even though horses and donkeys can mate and produce healthy offspring, those offspring cannot pass their genetic information down to future generations, so they are a genetic dead-end.
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