A 31-year-old pregnant woman has been sent by her doctor to check her immunity for varicella (chickenpox) following a local outbreak. this is a venipuncture indication.
Polymerase chain reaction (PCR) detection of VZV in skin lesions is the most accurate way to confirm a varicella diagnosis (vesicles, scabs, maculopapular lesions). The best places to sample are vesicular lesions or scabs if they are present.
It can be difficult to gather enough samples from maculopapular lesions in vaccine recipients. According to a comparison of samples taken from the same individuals who received a single dose of the vaccine, maculopapular lesions obtained using the right technique can be among the most reliable specimen types for identifying VZV.
Varicella is extremely contagious. Children are most likely to experience it.
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