A proton pump inhibitor is a medication that inhibits the ability of gastric cells to secrete hydrogen ions.
Gastric cells are the cells in the stomach mostly found in the pyloric region which are responsible for the release of enzymes for digestion of food. It includes mucous cells, parietal cells, chief cells and endocrine cells.
Parietal cells or oxyntic cells releases the hydrogen ion for maintaining the acidic condition of the cells.
Proton pump inhibitor is a medication that reduces the production of hydrogen ion in the stomach by inhibiting the H+/K+ATPase proton pump of the parietal cells.
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