A human karyotype with 46 normal chromosomes, including 22 pairs of autosomes, and xx sex chromosomes, represents a normal female.
An autosome is one of the 22 numbered pairs of chromosomes that utmost of us carry in nearly all of the cells of our body. We actually have a aggregate of 23 pairs of chromosomes in these cells, for a aggregate of 46 chromosomes,
Two of those are appertained to by letter rather than by number and are called sex chromosomes rather than autosomes, since they-- that is the X and Y chromosome-- help determine what sex, or gender, we are. The 22 pairs of autosomes are appertained to by number generally in inverse correlation with their size. That is, Chromosome 1, with the smallest number, is actually the largest chromosome.