Target organs include the heart, kidney, brain, and eyes. Hyperlipidemia and diabetes are risk factors for development of hypertension.
Target organs like the heart, kidneys, and brain are damaged as a result of prolonged exposure to high blood pressure. Due to the consequences of antihypertensive medications and cardiovascular aging, among groups having high cardiovascular risk, such damage to target organs may more accurately reflect exposure to high BP versus the BP value itself.
The following are examples of classic signs of untreated hypertensive end system damage: proteinuria, renal failure, retinopathy, vascular or hemorrhage stroke, retinopathy, coronary heart disease/myocardial infarction, including heart failure.
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