In large-scale genome-wide association studies, the researchers look for the genetic marker where in SNPs, one allele is found more often in people with a particular disorder than in healthy controls. So the correct option is B.
A sequence of DNA whose physical location on a chromosome is known is called a genetic marker. To find the responsible gene for an inherited disease, genetic markers are used.
The segments of DNA that are close to each other on a chromosome are usually inherited together in the offspring. Thus, the inheritance of a gene which is present nearby and has not yet been identified can be tracked by a genetic marker. It's important that the approximate location of that gene be known.
The genetic marker may be a coding sequence or a non-coding sequence of DNA.
Therefore the correct option is B.
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