Yearly vaccination of humans for influenza viruses is necessary because a rapid mutation in flu viruses alters the surface proteins in infected host cells
What is the pathogenesis of the influenza virus?
The influenza virus infects the respiratory tract directly or by immune system reaction damage.
- Only the respiratory epithelium in humans successfully cleaves the hemagglutinin (HA) molecule, resulting in infectious virus particles.
- Virus transmission happens when a vulnerable individual comes into touch with infected individuals' aerosols or respiratory fomites.
- The lung's failure to fulfil its fundamental function of gas exchange can be caused by a variety of factors, including airway blockage, loss of alveolar structure, loss of lung epithelial integrity due to direct epithelial cell death, and degradation of the essential extracellular matrix.
Acute pneumonia is identified in 30-40% of hospitalized patients with laboratory-confirmed influenza.
Hence, the correct answer is option D
Learn more about respiratory fomites here,
https://brainly.com/question/17463837
# SPJ4