The nurse's priority goal for the client enhance is myocardial oxygenation.
The amount of oxygen that is actually taken up (oxygen consumed) by the myocardium to support oxidative metabolism is greater than the amount that is actually delivered to the myocardium. Usually, the myocardium absorbs 50% of the oxygen that the arterial blood provides. The Fick Principle's description of the relationship between oxygen consumption and coronary blood flow determines this oxygen extraction. By definition, oxygen extraction is the difference between arterial and venous oxygen concentrations (CaO2-CvO2). The maximum amount of oxygen that can be extracted is 20 vol%, according to theory. However, due to the kinetics of oxygen dissociation from hemoglobin, the actual maximum oxygen extraction is only 15–16 vol%. Accordingly, the heart only uses about half to two-thirds of the physiologically available oxygen when it is functioning normally. In order to ensure adequate tissue oxygenation, the heart must tightly couple oxygen supply and demand.
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