The health care provider believes that the client has a deficiency in the leukocyte responsible for cell-mediated immunity & always looks for WBC count.
What is the role of a T-lymphocyte?
T cells are adaptive function regulators that act as major effectors in cell-mediated immunity. The TCR heterodimer receptor, which is formed via gene recombination, determines antigenic specificity.
• Differentiation of effector processes is enabled by recognition of given antigens in the context of major histocompatibility molecules and costimulatory molecules.
• Exogenous antigen delivered in the presence of MHC class II molecules is recognized by CD4+ T-helper lymphocyte cells. T-helper cell subtypes release distinct groups of cytokines that aid in functional activity.
• Cytotoxic T lymphocytes (CTLs), also known as CD8+ T lymphocytes, detect endogenous antigens presented in the presence of MHC class I molecules. CTLs directly destroy target cells by causing apoptosis via released premade proteins.
Learn more about T-Lymphocytes here,
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