Respuesta :

A and β, sticky

Amyloid plaques are collections of improperly folded proteins that develop between nerve cells. It is believed that these proteins with aberrant configurations are fundamental to Alzheimer's disease.

In the parts of the brain responsible for memory and other cognitive functions, amyloid plaques initially appear. Beta-amyloid protein fragments combine to produce amyloid plaques. The breakdown of a much bigger protein known as the amyloid precursor protein (APP) results in the production of beta-amyloid.

The 771 amino acids in APP are broken down by two enzymes to create beta-amyloid. Beta secretase and gamma secretase work together to split the big protein into bits of beta-amyloid, which can have 38, 40, or 42 amino acids.

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