The frequency of a mutant allele can change depending on the environment by breeding for advantageous traits and passing them on to children.
A variant of an allele found in the organism's wild type or standard form is called a mutant allele. Classically recognized mutant alleles (MAs) have been found to mainly reduce fitness, reduce fitness-related characteristics, and be partially recessive1,2,3. However, the majority of the genetic variance in complex traits is due to mutations with small effects.
According to traditional evolutionary theory, high mutation rate mutant alleles can fix in asexual populations through linkage with advantageous mutations. The frequency of mutators found in bacterial pathogens can be explained by this phenomenon, which has been experimentally demonstrated.
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