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Sister chromatids separate from one another and are pulled in different directions toward the ends of the cell during anaphase.

What are mitosis and its stages?

  • Mitosis is a process of cell division.
  • In mitosis, there are five phases.
  • Prophase, metaphase, anaphase, and telophase are different phases.
  • The fourth stage of mitotic cell division is anaphase.

What is anaphase in mitotic cell division?

  • The sister chromatids are separated during the anaphase of mitosis by two different methods.
  • The chromosomes are visible at the start of anaphase, and sister chromatids are linked at the centromere by a protein known as cohesin.
  • Chromosomes are held together by cohesin, which can be compared to glue.
  • Cohesin degradation must take place to separate the sister chromatids.
  • Considering that the centromere is involved in chromosomal mobility, it is referred to as a kinetochore.
  • The chromatid arms move after the kinetochore as the centromeres are drawn towards the opposing ends of the cell.
  • The spindle fibers and microtubules associated with each kinetochore start to shorten by shedding some of the subunits constituting their structure to promote the movement of the sister chromatids.

During anaphase, the sister chromatids split from one another. Then they are drawn to the opposite ends of the cell.

Learn more about anaphase here:

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