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The pre-mRNA contains introns and exons. Introns are the non-coding regions which might be removed from the mature mRNA. Exons are the protein-coding regions that are spliced together by the spliceosome after removal of the intron.
Pre-mRNA splicing is essential for gene expression in mammalian cells in which maximum protein-coding genes are disrupted by intervening sequences (introns). The process to get rid of introns is efficient and precise, consequently constituting the good sized majority of constitutive splicing activities in the cellular.
The pre-mRNA has to go through a few modifications to become a mature mRNA molecule that may go away the nucleus and be translated. These encompass splicing, capping, and addition of a poly-A tail, all of that may potentially be regulated – speeded up, bogged down, or altered to result in a extraordinary product.
Following transcription, new, immature strands of messenger RNA, referred to as pre-mRNA, may contain both introns and exons. The pre-mRNA molecule thus goes through a modification procedure inside the nucleus called splicing at some point of which the noncoding introns are reduce out and most effective the coding exons remain.
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