In theory, a poorly planned crossed aldol response can produce Four special Aldol Regioisomers.
Aldol response refers to a beneficial carbon-carbon bond forming response. This response is yet another instance of electrophilic substitution at the alpha carbon in enolate anions. since the enolates have a carbonian-like nature, they can easily upload to the carbonyls in a similar way as Grignard reagents are delivered.
The dimerization of the aldehyde (or ketone) to a beta-hydroxy aldehyde (or ketone) with the aid of alpha C-H addition of 1 reactant molecule to the carbonyl institution of the second reactant molecule, aldol regioisomers is the fundamental transformation of this response.
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