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The most common agent resulting in nephrotoxicity and subsequent acute tubular necrosis (ATN) in hospitalized patients is contrast media.
What is contrast media?
Imaging techniques employ contrast medium (CM) to highlight the variations between body tissues in pictures. The optimal contrast medium should be able to reach extremely high tissue concentrations without having any negative consequences.
What is nephrotoxicity?
Nephrotoxicity is defined as a rapid decline in kidney function brought on by the toxic effects of drugs and substances. There are numerous types, and some medications may have multiple negative effects on renal function. Nephrotoxic compounds are known as nephrotoxins.
Acute tubular necrosis: What is it?
Acute tubular necrosis (ATN) is a kidney condition that damages the kidneys' tubule cells and can result in acute renal failure. When blood flows through the kidneys, it is filtered by the tubules, which are small ducts.
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