When acetophenone was treated by one equivalent of LDA , followed by one equivalent of {tert}-butyl bromide give phenyl tert-butyl ketone as a most likely reaction products .
First LDA which is base abstract proton from methyl group ( less hindered site ) in acetophenone and form anion . Now this anion attack on t - butyl bromide and remove the bromide ion which is leaving group . And the final product will be phenyl tert-butyl ketone . In phenyl tert-butyl ketone the product contain phenyl group and tert-butyl group at each side of ketone .
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